COVID-19 VACCINE APPOINTMENT CENTER

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Vaccine Safety

Are COVID-19 vaccines safe?

All the COVID-19 vaccines being used have gone through rigorous studies to ensure they are as safe as possible. Systems that allow CDC to watch for safety issues are in place across the entire country.

The U.S. Food and Drug Administration (FDA) has granted Emergency Use Authorizations for COVID-19 vaccines that have been shown to meet rigorous safety criteria and be effective as determined by data from the manufacturers and findings from large clinical trials. Watch a video describing the emergency use authorization. Clinical trials for all vaccines must first show they meet rigorous criteria for safety and effectiveness before any vaccine, including COVID-19 vaccines, can be authorized or approved for use. The known and potential benefits of a COVID-19 vaccine must outweigh the known and potential risks of the vaccine. Learn more about how federal partners are ensuring the safety of COVID-19 vaccines in the United States.

Is it safe for me to get a COVID-19 vaccine if I am pregnant or breastfeeding?

People who are pregnant and part of a group recommended to receive the COVID-19 vaccine may choose to be vaccinated. If you have questions about getting vaccinated, talking with a healthcare provider may might help you make an informed decision. While breastfeeding is an important consideration, it is rarely a safety concern with vaccines.
No data are available yet on the safety of COVID-19 vaccines in lactating women or on the effects of mRNA vaccines on breastfed infants or on milk production/excretion. mRNA vaccines are not thought to be a risk to breastfeeding infants. People who are breastfeeding and are part of a group recommended to receive a COVID-19 vaccine, such as healthcare personnel, may choose to be vaccinated.

No data are available yet on the safety of COVID-19 vaccines in lactating women or on the effects of mRNA vaccines on breastfed infants or on milk production/excretion. mRNA vaccines are not thought to be a risk to breastfeeding infants. People who are breastfeeding and are part of a group recommended to receive a COVID-19 vaccine, such as healthcare personnel, may choose to be vaccinated.

To make sure that more information is gathered regarding the safety of these vaccines when administered during pregnancy, pregnant people are encouraged to enroll in v-safe, CDC’s new smartphone-based tool being used to check-in on people’s health after they receive a COVID-19 vaccine. If pregnant people report health events through v-safe after vaccination, someone from CDC may call to check on them and get more information. Additionally, pregnant people enrolled in v-safe will be contacted by CDC and asked to participate in a pregnancy registry that will monitor them through pregnancy and the first 3 months of infancy. Learn more about COVID-19 vaccination considerations for people who are pregnant or breastfeeding.
Is it safe for me to get a vaccine if I have an underlying medical condition?

People with underlying medical conditions can receive the FDA-authorized COVID-19 vaccines provided they have not had an immediate or severe allergic reaction to a COVID-19 vaccine or to any of the ingredients in the vaccine. Learn more about vaccination considerations for persons with underlying medical conditions. Vaccination is an important consideration for adults of any age with certain underlying medical conditions because they are at increased risk for severe illness from the virus that causes COVID-19.

Is there a risk of a severe allergic reaction if I receive the vaccine?

Serious problems from vaccination can happen, but they are rare. CDC has learned of reports that some people have experienced severe allergic reactions—also known as anaphylaxis—after getting a COVID-19 vaccine. As an example, an allergic reaction is considered severe when a person needs to be treated with epinephrine or EpiPen© or if they must go to the hospital. Learn more about COVID-19 vaccines and allergies.

How do I report it if I have a problem or bad reaction after getting a COVID-19 vaccine?

If you get a COVID-19 vaccine and you think you might be having a severe allergic reaction after leaving the vaccination site, seek immediate medical care by calling 911.

You can report side effects and reactions using either v-safe or the Vaccine Adverse Event Reporting System (VAERS.)

  • V-safe is a new smartphone-based, after-vaccination health checker for people who receive COVID-19 vaccines. V-safe uses text messaging and web surveys from CDC to check in with vaccine recipients following COVID-19 vaccination. V-safe also provides second vaccine dose reminders if needed, and telephone follow up to anyone who reports medically significant (important) adverse events.
  • Vaccine Adverse Event Reporting System (VAERS)external icon is the national system that collects reports from healthcare professionals, vaccine manufacturers, and the public of adverse events that happen after vaccination; reports of adverse events that are unexpected, appear to happen more often than expected, or have unusual patterns are followed up with specific studies. Reports to VAERS help CDC monitor the safety of vaccines. If experts detect an unexpected adverse event, they quickly study it further to assess whether it is a true safety concern. Experts then decide whether changes are needed in U.S. vaccine recommendations. This monitoring is critical to help ensure that the benefits continue to outweigh the risks for people who receive vaccines.

Healthcare providers will be required to report certain adverse events following vaccination to VAERS. Healthcare providers also have to adhere to any revised safety reporting requirements according to FDA’s conditions of authorized use throughout the duration of any Emergency Use Authorization; these requirements would be posted on FDA’s websiteexternal icon.

You can expect normal side effects after you are vaccinated. Refer to What to Expect at Your Appointment to Get Vaccinated for COVID-19 for additional information.

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